Publicações

(Publicações selecionadas)

Michaloski JS, Redondo AR, Magalhães LS, Cambui CC, Giordano RJ. (2016) Discovery of pan-VEGF inhibitory peptides directed to the extracellular ligand-binding domain of the VEGF receptors. Science Advances  2, no. 10, e1600611  (PubMed)

Beppler J, Mkaddem SB, Michaloski J, Honorato RV, Velasco IT, de Oliveira PS, Giordano RJ, Monteiro RC, Pinheiro da Silva F. (2016) Negative regulation of bacterial killing and inflammation by two novel CD16 ligands. Eur J Immunol. 46:1926-35. doi: 10.1002/eji.201546118. (PubMed)

Dreyfuss JL, Giordano RJ, Regatieri CV. (2015) Ocular Angiogenesis.J Ophthalmol. 2015:892043. (PubMed)

Sidman RL, Li J, Lawrence M, Hu W, Musso GF, Giordano RJ, Cardó-Vila M, Pasqualini R, Arap W. (2015) The peptidomimetic Vasotide targets two retinal VEGF receptors and reduces pathological angiogenesis in murine and nonhuman primate models of retinal disease. Sci Transl Med. 7(309):309ra165 (PubMed).

Teixeira AA, de Vasconcelos Vde C, Colli W, Alves MJ, Giordano RJ. (2015) Trypanosoma cruzi Binds to Cytokeratin through Conserved Peptide Motifs Found in the Laminin-G-Like Domain of the gp85/Trans-sialidase Proteins. PLoS Negl Trop Dis. 9(9):e0004099 (PubMed).

Pasqualini R.; Millikan R.E.; Christianson D.R.; Cardó-Vila M.; Driessen W.H.P.; Giordano R.J.; Hajitou A; Hoang A.G.; Wen S.; Barnhart K.F.; Baze W.B.; Marcott V.D.; Hawke D.H.; Do K., Navone N.M; Efstathiou E.; Troncoso P.; Lobb R.L.; Logothetis C.J. and Arap W. Targeting the Interleukin-11 Receptor in Metastatic Prostate Cancer: A First-in-Man Study. Cancer, 121(14):2411-21(PubMed).

Porto G., Giordano, RJ, Marti, LC, Stolf, B, Pasqualini, R, Arap, W, Kalil, J, Coelho, V Identification of novel immunoregulatory molecules on human thymic regulatory CD4+CD25+ T cells by phage display. PLoS ONE 6(8): e21702. doi:10.1371/journal.pone.0021702. (PlosONE)

Tonelli RR, Giordano RJ, Barbu E, Torrecilhas AC, Kobayashi GS, Langley RR, Arap W, Pasqualini R, Colli W and Alves MJM (2010) Role of the gp85/trans-sialidases in Trypanosoma cruzi tissue tropism: preferential binding of a conserved peptide motif to the vasculature in vivo. Plos Negl Trop Dis, 4, e864. (PubMed)

Giordano R.J., Cardó-Vila, M., Salameh, A., Anobom, C.D., Zeitlin, B.D., Hawke, D.H., Valente, A.P., Almeida, F.C., Nör, J.E., Sidman, R.L., Pasqualini, R. and Arap, W. (2010) From combinatorial peptide selection to drug prototype (I): targeting the vascular endothelial growth factor receptor pathway. Proc Natl Acad Sci U S A. 107, 5112-7. (PubMed)

Cardó-Vila, M., Giordano RJ, Sidman, R.L., Bronk, L.F., Fan, Z., Mendelsohn, J., Arap, W. and Pasqualini, R. (2010) From combinatorial peptide selection to drug prototype (II): targeting the epidermal growth factor receptor pathway. Proc Natl Acad Sci U S A. 107, 5118-23. (PubMed)

Dias-Neto, E., Nunes, D.N., Giordano, R.J., Sun, J., Botz, G.H., Yang, K., Setubal, J.C., Pasqualini, R. and Arap, W. (2009) Next-generation phage display: integrating and comparing available molecular tools to enable cost-effective high-throughput analysis. PLoS One 4(12):e8338. (PubMed)

Giordano RJ, Edwards JK, Tuder RM, Arap W, Pasqualini R. (2009) Combinatorial ligand-directed lung targeting. Proc Am Thorac Soc 6: 411-5. (PubMed)

Cardó-Vila M, Zurita AJ, Giordano RJ, Sun J, Rangel R, Guzman-Rojas L, Anobom CD, Valente AP, Almeida FC, Lahdenranta J, Kolonin MG, Arap W, Pasqualini R.  (2008) A ligand peptide motif selected from a cancer patient is a receptor-interacting site within human interleukin-11. PLoS One. 3(10): e3452. (PubMed)

Giordano RJ, Lahdenranta J, Zhen L, Chukwueke U, Petrache I, Langley RR, Fidler IJ, Pasqualini R, Tuder RM, Arap W. (2008) Targeted induction of lung endothelial cell apoptosis causes emphysema-like changes in the mouse. J Biol Chem. 283: 29447-60. (PubMed)

Giordano RJ. (2008) Heparanase-2 and syndecan-1 in colon cancer: the ugly ducklings or the beautiful swans? Eur J Gastroenterol Hepatol. 20:716-8. (PubMed)

Giordano RJ, Anobom CD, Cardó-Vila M, Kalil J, Valente AP, Pasqualini R, Almeida FC, Arap W. (2005) Structural basis for the interaction of a vascular endothelial growth factor mimic peptide motif and its corresponding receptors. Chem Biol. 12: 1075-83. (PubMed)

Arap W, Kolonin MG, Trepel M, Lahdenranta J, Cardó-Vila M, Giordano RJ, et al. (2002) Steps toward mapping the human vasculature by phage display. Nat Med. 8: 121-7. (PubMed)

Almeida FC, Amorim GC, Moreau VH, Sousa VO, Creazola AT, Américo TA, Pais AP, Leite A, Netto LE, Giordano RJ, Valente AP. (2001) Selectively labeling the heterologous protein in Escherichia coli for NMR studies: a strategy to speed up NMR spectroscopy. J Magn Reson. 148:142-6. (PubMed)

Giordano RJ, Cardó-Vila M, Lahdenranta J, Pasqualini R, Arap W. (2001) Biopanning and rapid analysis of selective interactive ligands. Nat Med. 7: 1249-53. (PubMed)

Magdesian MH, Giordano R, Ulrich H, Juliano MA, Juliano L, Schumacher RI, Colli W, Alves MJ. (2001) Infection by Trypanosoma cruzi. Identification of a parasite ligand and its host cell receptor. J Biol Chem. 276: 19382-9. (PubMed)

Giordano R, Fouts DL, Tewari D, Colli W, Manning JE, Alves MJ.  (1999) Cloning of a surface membrane glycoprotein specific for the infective form of Trypanosoma cruzi having adhesive properties to laminin. J Biol Chem. 274: 3461-8. (PubMed)

Giordano R, Chammas R, Veiga SS, Colli W, Alves MJ. (1994) An acidic component of the heterogeneous Tc-85 protein family from the surface of Trypanosoma cruzi is a laminin binding glycoprotein. Mol Biochem Parasitol. 65: 85-94. (PubMed)